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Twenty Twenty Therapeutics

#37,556 H-1B sponsor of 76,738#831 Pharma & biotech sponsor of 1,270
H-1B Visa Sponsorship 2026

Pharma & biotech Β· H-1B sponsor Β· FY2017–2026

🏒 South San Francisco, CA HQ

Does Twenty Twenty Therapeutics sponsor H-1B visas and green cards?

Yes. Twenty Twenty Therapeutics has filed 9 H-1B LCAs and 1 PERM green-card case with the U.S. Department of Labor between FY2020 and FY2026. In FY2024 Twenty Twenty Therapeutics filed 1 H-1B LCA at a median base salary of $162,750, and 1 green-card case was decided.

It files most often for Hardware Engineer - Ophthalmology Drug-Dispensing Smart Lens roles, most in South San Francisco, CA.

H-1B filings
9
(FY2020–2024)
Median base pay
$163k
from 1 filing (FY2024)
Pay vs market
+43%
above national median ($114k, FY2024)
Green-card (PERM) filings
1
(FY2025)

H-1B pay & filings by year

Median base salary (line) and H-1B filing volume (bars), by fiscal year

Show the numbers behind this chart
Twenty Twenty Therapeutics LLC H-1B LCA filings and median base salary by fiscal year
Fiscal yearH-1B LCA filingsMedian base salary
FY20241$163k
FY20231$151k
FY20222$174k
FY20205$152k

H-1B wage floor & filing outcomes

What this employer pays against the DOL legal minimum, how senior the roles are, and how the filings were decided

Pay vs the legal floor
$152k
20% above the $127k prevailing wage
Role seniority (wage levels)
56% entry to mid
513
LCA decisions
88.9% certified
8 of 9 filings
Withdrawn 1
USCIS I-129 petition outcomes Β· FY2017–2023
Approved4 petitions
Denied2 petitions
LCA filings by type Β· FY2020–2024
New employment6 filings66.7%
Transfers in2 filings22.2%
Renewals1 filings11.1%

Green-card (PERM)

1 green-card (PERM) filing in FY2025, median offer $101k. Too few years to chart a trend.

Worker backgrounds

From green-card (PERM) cases

1 green-card (PERM) case, from FY2025. DOL stopped publishing worker details that year.

Patents

Granted
26
US patents
Published, not yet granted
82
applications
Most recent grant
November 11, 2025
Top area
Filters implantable into blood vessels; prostheses11
Other top areas
Diagnosis; surgery; identification4Electrotherapy; magnetotherapy; radiation therapy4Optical elements2Macromolecular compounds obtained by reactions only1

Pay against the local market

Twenty Twenty Therapeutics’s most-filed occupations and metros, FY2020–FY2024. Its median base salary is 120% of the local BLS median for the same work.

OccupationMetroFilingsTwenty Twenty Therapeutics payLocal BLS median‑vs market
Bioengineers and Biomedical EngineersSan Francisco, CA3$152,000$123,480123%
Electrical EngineersSan Francisco, CA2$174,040$130,345134%
Mechanical EngineersSan Francisco, CA2$151,500$130,245116%
Software DevelopersSan Francisco, CA2$176,375$168,438105%

About Twenty Twenty Therapeutics

Name (DOL filings)
Twenty Twenty Therapeutics LLC
Listed
β€”
Sponsoring since
FY2020
Main filing location
South San Francisco, CA
Industry
Pharma & biotech
Employees (global)
β€”
H-1B filings
9
Median base
$152,000
R&D
β€”

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